Penumbra, Inc.

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About Penumbra, Inc.

Founded in 2004 and headquartered in Alameda, California, Penumbra, Inc. is a global medical device company dedicated to innovative treatments for neurovascular and peripheral vascular diseases. The company designs, develops, manufactures, and markets devices for ischemic and hemorrhagic stroke, pulmonary embolism, and peripheral vascular conditions. Penumbra is particularly recognized for its leadership in thrombectomy technologies, including the Penumbra System™ aspiration catheter and the Lightning™ intelligent aspiration system.

Core Business & Key Technologies

Penumbra’s business centers on neurovascular and peripheral vascular interventions. Its technologies include aspiration-based thrombectomy systems, embolization coils, and advanced access platforms. Products such as the Penumbra System™ and Indigo System™ address blood clot removal, while the Ruby Coil™ supports embolization procedures. The REAL Neuro System™ enhances real-time imaging and navigation during complex neurointerventions. Additionally, Penumbra develops virtual reality–based rehabilitation and cognitive therapy tools to support patient recovery.

Market Position & Flagship Products

Penumbra holds a strong global position in neurovascular intervention. Flagship solutions include the Penumbra System™ for acute ischemic stroke, the Lightning™ Flash Aspiration System for rapid thrombectomy, and the Ruby Embolization Platform XL System, featuring the world’s largest detachable embolization coils (as of May 2025). The REAL Neuro System™ improves surgical precision, while new innovations such as the swiftPAC™ coil line expand treatment options and clinical applications.