Given Imaging, Inc.

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Company Overview

Given Imaging, Inc., headquartered in Yokneam Illit, Israel, is a world-leading medical technology company specializing in capsule endoscopy systems for gastrointestinal (GI) imaging. Founded in 1998 by Gavriel Meron and Rafael Development Corporation, it pioneered capsule endoscopy technology, marketed globally through its subsidiary Sierra Scientific Instruments. Acquired by Covidien in 2013 and subsequently by Medtronic in 2015, Given Imaging employs approximately 800 staff and has marketed its products in over 60 countries. Its CEO is Homi Shamir.

Core Business and Product Pipeline

Given Imaging develops and commercializes capsule endoscopy systems and GI diagnostic tools. Its proprietary PillCam systems enable noninvasive visualization of the GI tract. Key products include:
PillCam SB (Small Bowel): First capsule endoscopy model for small bowel visualization, requiring bowel preparation but no sedation.
PillCam ESO: Capsule for esophagus visualization.
PillCam COLON: Complements traditional colonoscopy, suitable for incomplete or contraindicated procedures.
PillCam CROHN’S: Visualizes small bowel and colonic mucosa noninvasively.
Bravo pH Monitoring System: Wireless, catheter-free system for gastroesophageal reflux disease (GERD) diagnosis.
Agile Patency System: Assesses GI tract patency to ensure safe capsule passage.

Market Position and Key Products

Given Imaging is a global leader in GI medical devices, with its PillCam platform recognized as the gold standard for capsule endoscopy. Over one million patients worldwide have benefited from its technologies, which include high-resolution manometry and pH monitoring. The company’s comprehensive GI diagnostic solutions enhance visualization, diagnosis, and patient care.

Research and Innovation

Given Imaging leverages advanced technologies, including MATLAB and Image Processing Toolbox, to develop and refine its PillCam capsules. The disposable capsules contain miniaturized cameras, batteries, antennas, and transmitters, capturing up to 50,000 images over eight hours. Images are processed via proprietary RAPID® software for physician review. Continuous R&D focuses on image enhancement, segmentation, classification, and improving capsule performance.